NexTech 2021 Congress
October 03, 2021 to October 07, 2021 - Barcelona, Spain

  • UBICOMM 2021, The Fifteenth International Conference on Mobile Ubiquitous Computing, Systems, Services and Technologies
  • ADVCOMP 2021, The Fifteenth International Conference on Advanced Engineering Computing and Applications in Sciences
  • SEMAPRO 2021, The Fifteenth International Conference on Advances in Semantic Processing
  • AMBIENT 2021, The Eleventh International Conference on Ambient Computing, Applications, Services and Technologies
  • EMERGING 2021, The Thirteenth International Conference on Emerging Networks and Systems Intelligence
  • DATA ANALYTICS 2021, The Tenth International Conference on Data Analytics
  • GLOBAL HEALTH 2021, The Tenth International Conference on Global Health Challenges
  • CYBER 2021, The Sixth International Conference on Cyber-Technologies and Cyber-Systems

SoftNet 2021 Congress
October 03, 2021 to October 07, 2021 - Barcelona, Spain

  • ICSEA 2021, The Sixteenth International Conference on Software Engineering Advances
  • ICSNC 2021, The Sixteenth International Conference on Systems and Networks Communications
  • CENTRIC 2021, The Fourteenth International Conference on Advances in Human-oriented and Personalized Mechanisms, Technologies, and Services
  • VALID 2021, The Thirteenth International Conference on Advances in System Testing and Validation Lifecycle
  • SIMUL 2021, The Thirteenth International Conference on Advances in System Simulation
  • SOTICS 2021, The Eleventh International Conference on Social Media Technologies, Communication, and Informatics
  • INNOV 2021, The Tenth International Conference on Communications, Computation, Networks and Technologies
  • HEALTHINFO 2021, The Sixth International Conference on Informatics and Assistive Technologies for Health-Care, Medical Support and Wellbeing

NetWare 2021 Congress
November 14, 2021 to November 18, 2021 - Athens, Greece

  • SENSORCOMM 2021, The Fifteenth International Conference on Sensor Technologies and Applications
  • SENSORDEVICES 2021, The Twelfth International Conference on Sensor Device Technologies and Applications
  • SECURWARE 2021, The Fifteenth International Conference on Emerging Security Information, Systems and Technologies
  • AFIN 2021, The Thirteenth International Conference on Advances in Future Internet
  • CENICS 2021, The Fourteenth International Conference on Advances in Circuits, Electronics and Micro-electronics
  • ICQNM 2021, The Fifteenth International Conference on Quantum, Nano/Bio, and Micro Technologies
  • FASSI 2021, The Seventh International Conference on Fundamentals and Advances in Software Systems Integration
  • GREEN 2021, The Sixth International Conference on Green Communications, Computing and Technologies

TrendNews 2021 Congress
November 14, 2021 to November 18, 2021 - Athens, Greece

  • CORETA 2021, Advances on Core Technologies and Applications
  • DIGITAL 2021, Advances on Societal Digital Transformation

 


ThinkMind // BIOTECHNO 2016, The Eighth International Conference on Bioinformatics, Biocomputational Systems and Biotechnologies // View article biotechno_2016_2_10_60012


Using a Synthetic Probe to Study the Robustness of the Segregation Process of Protein Aggregates in Escherichia coli

Authors:
Andre Ribeiro
Samuel Oliveira

Keywords: segregation; polar retention; protein aggregates; cold temperature conditions; synthetic probes; cell lineages;

Abstract:
Even though the processes of protein production and folding are not immune to errors, Escherichia coli lineages are capable to maintain a stable cell lineage, provided viable environmental conditions. One of the internal processes that makes this possible consists of segregating unwanted protein aggregates to the cell poles by nucleoid exclusion, which, combined with cell divisions, generates asymmetries in the aging process of the population, with some individuals aging faster while others exhibit rejuvenation. A recent study showed that this process is not immune to sub-optimal temperature conditions due to increased cytoplasm viscosity, which weakens the anisotropy in aggregate displacements at the nucleoid borders. This was made possible by the usage of a synthetic fluorescent probe, consisting of a RNA sequence with multiple binding sites for the MS2-GFP synthetic protein, which can be tracked in time-lapse microscopy images. Here we provide a description of the findings from these measurements and investigate with an In Silico model the consequences in the context of cell lineages.

Pages: 21 to 22

Copyright: Copyright (c) IARIA, 2016

Publication date: June 26, 2016

Published in: conference

ISSN: 2308-4383

ISBN: 978-1-61208-488-6

Location: Lisbon, Portugal

Dates: from June 26, 2016 to June 30, 2016

SERVICES CONTACT
2010 - 2017 © ThinkMind. All rights reserved.
Read Terms of Service and Privacy Policy.